Childhood sclerodermatomyositis with generalized morphea

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Fasciitis associated with generalized morphea.

Figure 1. Photograph of the legs. A large, thickened, firm, hyper/hypopigmented plaque is evident on the left leg. Figure 2. Biopsies of affected skin (A) and contiguous tibialis anterior muscle and fascia from the left leg (B–D). (A) The der-mal collagen is thickened, packed, and hyalinized. The subcutaneous fat is extensively replaced by collagen, and perivascular inflammatory infiltrates are...

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Generalized morphea: a case report.

Generalized morphea is a subtype of localized scleroderma that lacks systemic manifestations. It is a rare condition in which idiopathic sclerosis of the skin occurs in a widespread manner. We report a 37-year old Thai female who presented with multiple hypopigmented lesions on right leg and right arm with a skin biopsy showing the typical sclerotic change. The patient responded to treatment wi...

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Generalized Morphea: a Case Report

Generalized morphea is a subtype of localized scleroderma, which lacks systemic manifestations and displays widespread, multiple, well-circumscribed, indurated plaques. We represent a 46-year-old woman with generalized morphea. More than 3 years ago she developed multiple, nonpruritic plaques symmetrically on the trunk and extremities. The patient’s clinical history, laboratory analysis and his...

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Unilateral generalized morphea: A case report

Morphea is a localized form of scleroderma characterized by sclerotic plaques limited to the skin. Although its cause is unknown, genetic, infectious and autoimmune mechanisms have been suggessed in the pathogenesis of the morphea. It is more common among childen and young women. Although the prognosis is generally good, it sometimes causes significant morbidity. Morphea has five subtypes as pl...

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Ultrasound monitoring of childhood linear morphea.

intense the granular deposits, the slower and more persistent the course of the disease, whereas a diffuse pattern of pigmentation with an absence of globules or dots was associated with earlier resolution.9,10 In our patient we observed a mottled pattern formed by clusters of numerous brown dots and globules and, as predicted, the course clinical was slow and the condition persisted for a year...

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ژورنال

عنوان ژورنال: Indian Journal of Dermatology, Venereology and Leprology

سال: 2008

ISSN: 0378-6323

DOI: 10.4103/0378-6323.39702